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A detailed multi-omics analysis of GNB2 gene in human cancers.
Zhang L, Sahar AM, Li C, Chaudhary A, Yousaf I, Saeedah MA, Mubarak A, Haris M, Nawaz M, Reem MA, Ramadan FA, Mostafa AAM, Feng W, Hameed Y. Zhang L, et al. Braz J Biol. 2022 Jun 17;84:e260169. doi: 10.1590/1519-6984.260169. eCollection 2022. Braz J Biol. 2022. PMID: 35730811 Free article.
The Guanine-nucleotide binding protein 2 (GNB2) encodes for beta2 subunit (Gbeta2) of the G-protein complex. ...As well, the elevated expression of GNB2 was found to be associated with the reduced overall survival (OS) of the Liver Hepatocellular Carcinoma (L …
The Guanine-nucleotide binding protein 2 (GNB2) encodes for beta2 subunit (Gbeta2) of the G-protein complex. ...As well, the elevated …
Predicting Novel Drug Candidates for Pancreatic Neuroendocrine Tumors via Gene Signature Comparison and Connectivity Mapping.
Xiao Y, Xu G, Cloyd JM, Du S, Mao Y, Pawlik TM. Xiao Y, et al. J Gastrointest Surg. 2022 Aug;26(8):1670-1678. doi: 10.1007/s11605-022-05337-6. Epub 2022 May 4. J Gastrointest Surg. 2022. PMID: 35508682
In particular, the protein-protein interaction analysis revealed 10 upregulated hub genes (DYNLL1, GNB5, GNB2, GNG4, GNAI2, GNAI1, HIST2H2BE, NUP107, NUP133, and SNAP25) and 10 downregulated hub genes (CXCL8, F2, CXCL2, GCG, SST, INS, GALR3, CCL20, ADRA2B, and CXCL6). ...
In particular, the protein-protein interaction analysis revealed 10 upregulated hub genes (DYNLL1, GNB5, GNB2, GNG4, GNAI2, GNAI1, HI …